Long term benefit of treating Posttraumatic Stress Disorder (PTSD) with MDMA-assisted Psychotherapy

SAGE Insight

Durability of Improvement in PTSD Symptoms and absence of harmful effects or drug dependency after MDMA-assisted Psychotherapy: A Prospective Long-Term Follow-up Study

From Journal of Psychopharmacology

Posttraumatic Stress Disorder (PTSD) can be a chronic, severely disabling condition. Existing pharmacological and psychotherapeutic treatments for PTSD are effective for many but not all sufferers, a need for research into a wider array of more effective treatments is widely recognized.  Over a decade ago, the authors conceived a study in an attempt to develop and test a novel therapy for PTSD. This follow up workreports very long-term outcome results in the original cohort demonstrating sustained benefit over time, no cases of subsequent drug abuse and no reports of neurocognitive declines. The impressive results indicate a favorable long-term risk/benefit ratio for PTSD treatment with a few doses of pure MDMA administered in a supportive setting in conjunction with psychotherapy.

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